Daily Archives: January 17, 2022

16 posts

Mesh Generation

Once an anatomical model is constructed in the form of an implicit surface a mesh must be generated to perform the numerical simulations. For this reason we also develop a tool to generate suitable grids for CFD simulations. This step is critical since the mesh can change the  accuracy of the numerical […]

Image Segmentation and Processing

Medical images are often affected by noise or artifacts. A MOX research topic concerns the reduction of metal artifacts (MAR) in X-ray computerized tomography (CT), and the development of techniques and procedures for the pre-processing of medical images. A second focus is the generation of automatic methods for the segmentation of different vessel district […]

Bicuspid Aortic Valve Deseases

Bicuspid aortic valve (BAV) is the most common congenital heart disease. Itis related to an increased prevalence of ascending aortic dilatation and aneurysm in normally functioning valvular regime when compared to tricuspid aortic valve (TAV). The pathogenesis of aortic dilatation in patients with BAV is nowadays uncertain. A first hypothesis postulates a genetic origin for these […]

Atherosclerosis in Carotids

The carotid bifurcation is one of the preferential site of plaque formation, leading to vessel stenosis, and, possibly, to a complete obstruction of the vessel, formation of blood clots and breakage with embolization of fragments into the brain tissue. For these reasons, carotid endarterectomy (CEA), consisting in the surgical removal of the plaque, is intensively used in the clinical practice. The research […]

Abdominal Aortic Aneurysms

The abdominal aorta is one of the preferential site of aneurysm formation. Abdominal aortic aneurysms (AAA) represent 83 % of all non-cerebral aneurysms diagnosed in the United States. Untreated AAAs may rupture a severe clinical event associated with high rate of mortality and morbidity. The research at MOX focused on the fluid-dynamics in AAA. In […]

Heart Integration

Electromechanical coupling Modeling the heart contraction leads to the solution of a coupled problem between the electrical model, which describes the propagation of the electrical signal that triggers the heart contraction, and the mechanical model, that describes the cardiac deformations. Beside the direct effect of the electrical activity in the mechanics, it is relevant to model also the feedback of the mechanics in the […]