Persistence diagrams for exploring the shape variability of abdominal aortic aneurysms

Keywords

Statistics
Statistical learning
Health Analytics
Living Systems and Precision Medicine
Code:
16/2024
Title:
Persistence diagrams for exploring the shape variability of abdominal aortic aneurysms
Date:
Monday 12th February 2024
Author(s):
Domanin D. A.; Pegoraro M.; Trimarchi S.; Domanin M.; Secchi P.
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Abstract:
Abdominal Aortic Aneurysm consists of a permanent dilation in the abodminal portion of the aorta and, along with its associated pathologies like calcifications and intraluminal thrombi, is one of the most important pathologies of the circulatory system. The shape of the aorta is among the primary drivers for these health issues, with particular reference to all the characteristics which affects the hemodynamics. Starting from the computed tomography angiography of a patient, we propose to summarize such information using tools derived from Topological Data Analysis, obtaining persistence diagrams which describe the irregularities of the lumen of the aorta. We showcase the effectiveness of such shape-related descriptors with a series of supervised and unsupervised case studies.
This report, or a modified version of it, has been also submitted to, or published on
Arxiv