Numerical approximation of the electromechanical coupling in the left ventricle with inclusion of the Purkinje network
Keywords
Computational Medicine for the Cardiocirculatory System
Code:
58/2017
Title:
Numerical approximation of the electromechanical coupling in the left ventricle with inclusion of the Purkinje network
Date:
Thursday 2nd November 2017
Author(s):
Landajuela, M.; Vergara, C.; Gerbi, A.; Dede', L.; Formaggia, L.; Quarteroni, A.
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Abstract:
In this work, we consider the numerical approximation of the electromechanical
coupling in the left ventricle with inclusion of the Purkinje network.
The mathematical model couples the 3D elastodynamics and bidomain
equations for the electrophysiology in the myocardium with the 1D
monodomain equation in the Purkinje network. For the numerical solution
of the coupled problem, we consider a fixed-point iterative algorithm that
enables a partitioned solution of the myocardium and Purkinje network
problems. Different levels of myocardium-network splitting are considered
and analyzed. The results are compared with those obtained using standard
strategies proposed in the literature to trigger the electrical activation. Finally,
we present a physiological cardiac simulation, including the initiation
of the signal in the Purkinje network, the systolic phase and the beginning
of the filling phase.