Multiscale modeling and simulation of drug release from cardiovascular stents
Keywords
Advanced Numerical Methods for Scientific Computing
Computational Medicine for the Cardiocirculatory System
Living Systems and Precision Medicine
Code:
15/2007
Title:
Multiscale modeling and simulation of drug release from cardiovascular stents
Date:
Tuesday 16th October 2007
Author(s):
Vergara, Christian; Zunino, Paolo
Download link:
Abstract:
In this study, we focus on a specific application, the modeling and simulation of drug release from cardiovascular drug eluting stents.
In particular, we analyze the drug release dynamics from the stent coating, where the drug is initially stored, to the arterial wall surrounding the stent. The main challenge in addressing this problem consists in accounting for multiple space scales.
We propose a new multiscale model for the drug release that significantly cuts down the computational cost. This model allows us to consider a realistic problem setting, which is applied for the numerical experiments.