A computational study of blood flow dynamics in the pulmonary arteries
Sunday 28th November 2021
Marcinno, F.; Zingaro, A.; Fumagalli, I.; Dede', L.; Vergara, C.
In this work we study for the first time the blood dynamics in the pulmonary arteries by means of a 3D-0D geometric multiscale approach, where a detailed 3D model for the pulmonary arteries is coupled with a lumped parameters (0D) model of the cardiocirculatory system. We propose to investigate two strategies for the numerical solution of the 3D-0D coupled problem: a Splitting Algorithm, where information are exchanged between 3D and 0D models at each time step at the interfaces, and a One-Way Algorithm, where the 0D is solved first off-line. In our numerical experiments performed in a realistic patient-specific 3D domain with a physiologically calibrated 0D model, we discuss first the issue on instabilities that may arise when not suitable connections are considered between 3D and 0D models; second we compare the performance and accuracy of the two proposed numerical strategies. Finally, we report a comparison between an healthy and an hypertensive case, providing a preliminary result highlighting how our method could be used in future for clinical purposes.