|Abstract:|| The arteriovenous fistula (AVF) is the main form of vascular access for
hemodialysis patients, but its maintenance is very challenging. Its failure
is mainly related to intimal hyperplasia, leading to stenosis.
The aim of this work is twofold: i) to perform a computational study for
the comparison of the disturbed blood dynamics in different configurations
of AVF and ii) to assess the amount of turbulence developed by the specific
geometric configuration of AVF.
To this aim, we reconstructed realistic 3D geometries of two patients
with a side-to-end AVF, performing a parametric study by changing the
angle of incidence at the anastomosis. We solved the incompressible Navier-
Stokes equations modeling the blood as an incompressible and Newtonian
fluid. Large Eddy Simulations (LES) were considered to capture the tran-
sition to turbulence developed at the anastomosis. The values of prescribed
boundary conditions are obtained from clinical Echo-Color Doppler mea-
To assess the disturbed flow, we considered hemodynamic quantities
such as the velocity field, the pressure distribution, and wall shear stresses derived quantities, whereas to quantify the transition to turbulence, we computed the standard deviation of the velocity field among different heartbeates and the turbulent kinetic energy.