A fast cardiac electromechanics model coupling the Eikonal and the nonlinear mechanics equations

Code:
59/2021
Title:
A fast cardiac electromechanics model coupling the Eikonal and the nonlinear mechanics equations
Date:
Monday 27th September 2021
Author(s):
Stella, S.; Regazzoni, F.; Vergara, C.; Dede', L.; Quarteroni, A.
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Abstract:
We present a new model of human cardiac electromechanics for the left ventricle where electrophysiology is described by a Reaction-Eikonal model and which enables an off-line resolution of the reaction model, thus entailing a big saving of computational time. Subcellular dynamics is coupled with a model of tissue mechanics, which is in turn coupled with a windkessel model for blood circulation. Our numerical results show that the proposed model is able to provide a physiological response to changes in certain variables (end-diastolic volume, total peripheral resistance, contractility). We also show that our model is able to reproduce with high accuracy (and with a considerably lower computational time) the results that we would obtain if the monodomain model should be used in place of the Eikonal model.